Start-up brings mobile app for detection and risk assessment of COVID 19

Bangalore, July 28, 2020: Novel methods to supplement early detection of disease and risk assessment of infected population is a crucial challenge the COVID 19 pandemic has thrown up.

The Centre for Augmenting WAR with COVID-19 Health Crisis (CAWACH) has selected Bangalore based startup Acculi Labs to develop a COVID risk assessment profile called Lyfas COVID score.

Acculi Labs is armed with ‘Lyfas’ a clinical-grade, non-invasive, digital functional biomarker smartphone tool for screening, early detection, root cause analysis, acute event risk assessment, prognosis, and home monitoring of chronic diseases which they have repurposed to Lyfas COVID score.

CAWACH, an initiative by the National Science & Technology Entrepreneurship Development Board , is supporting market-ready innovations for the control of COVID-19 and startup ideas

The new technology developed with support from the DST, will detect possible infection in an asymptomatic individual to prioritise the conventional testing queue as well as carry out a risk assessment of an asymptomatic individual to become symptomatic and risk assessment of an asymptomatic individual for recovery.
Lyfas has received a grant of Rs 30 Lakh from DST and is now virtually supported by IIT Madras, Healthcare Technology Innovation Centre (HTIC), MedTech Incubator.

Lyfas is an Android application in which, when one keeps the index finger on the rear phone camera of a mobile phone for 5 minutes, captures the capillary pulse and blood volume change and derive 95 biomarkers with proprietary algorithms and signal processing techniques.

It uses the power of smartphone processor and smartphone sensors to capture a bunch of body signals.

The signals are subsequently processed on the principle of Photoplethysmography(PPG), Photo Chromatography(PCG), Arterial Photoplethysmography(APPG), mobile spirometry and Pulse Rate Variability(PRV).
Lyfas then provides cardio-respiratory, cardio-vascular, hematology, hemorheology, neurology based parameters that are capable of tracking minute pathophysiological changes in the body.

These changes are further profiled into the organ system-wide response.
The technology is focused on population screening, monitoring of quarantined individuals and surveillance at the community spreading phase.

It has been proved to detect asymptomatic individuals with an accuracy of 92%, specificity of 90% and a sensitivity of 92% in a study conducted with Medanta Medicity hospital.

Witnessing the success of the study, Medanta ethics committee has approved it for a larger population study.

This study is currently registered in Clinical Trials Registry- India (CTRI) and is acknowledged by World Health Organisation (WHO).

While Aarogya Setu works on contact tracing where one has to enter your symptoms, Lyfas is a proper medical screening test which purely depends upon test results.

“Inexpensive, accessible, point-of-care smart phone based diagnostics is a powerful tool that would tremendously help in screening the high risk cases, sustained monitoring of quarantined cases and general surveillance. Lyfas is an interesting example of the rising power of technology startups in innovating relevant and creative solutions for the emergent challenges with speed and efficacy,” said Prof Ashutosh Sharma, Secretary, DST.

The clinical trials and regulatory proceedings are expected to be completed by the end of September, after which the testing facility will be made available for the general public.

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